Health and population effects of rare gene knockouts in adult humans with related parents
Vagheesh Narasimhan, Karen Hunt, Dan Mason, Christopher L Baker, Konrad Karczewski, Michael Barnes, Anthony Barnett, Chris Bates, Srikanth Bellary, Nick Bockett, Kristina Giorda, Chris Griffiths, Harry Hemingway, Zhilong Jia, Ann Kelly, , David van Heel
The paper estimates the health effects of rare gene knockouts in adults by analyzing exome sequencing data and health records, finding no significant disease associations.
Science · Apr 22, 2016Peer-reviewedGenomics