Author

Christopher Letson

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Abigail AjaneliD· 1 shared Craig N. MorrelliD· 1 shared Ei Thanda TuniD· 1 shared Jorge Di PaolaiD· 1 shared Joshua I. SineriD· 1 shared Kimsey PlatteniD· 1 shared Lilian AntunesiD· 1 shared Mary C. Fulbright· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Abigail AjanelORCID

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1 paper

Recent·Most cited

TNFα drives platelet hyperreactivity and thromboinflammation through regulation of hematopoietic stem and progenitor cells.

Joshua I. Siner, Molly Brakhane, Kimsey Platten, Abigail Ajanel, Ei Thanda Tun, Lilian Antunes, Thomas Girard, Nina M. Lasky, Mary C. Fulbright, Christopher Letson, Yoon-A Kang, Craig N. Morrell, Stephen T. Oh, Jorge Di Paola

This study shows TNFα increases platelet reactivity and thromboinflammation by expanding and reprogramming hematopoietic stem and progenitor cells, not directly affecting megakaryocytes.

bioRxiv · Sep 29, 2026 · PreprintCell Biology