The 4T1 breast carcinoma model possesses hybrid epithelial/mesenchymal traits linked to a highly metastatic phenotype
Mary E. Herndon, Katherine Gibson-Corley, Lori L. Wallrath, Michael D. Henry, Christopher S. Stipp
This study investigates E-cadherin's role in 4T1 breast carcinoma metastasis, finding that E-cadherin is retained and does not determine metastatic capacity, with cells displaying hybrid epithelial/mesenchymal traits.
bioRxiv · Feb 2, 2024 · PreprintCancer Biology