Author

Christos Botos

Leiden University Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:batch correction / integration· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1 Assay:imaging· 1 Assay:metabolomics· 1 Organism:mouse· 1 Research Focus:software / tool· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Ahmed Essam MahfouziD· 1 shared Benedetta ManzatoiD· 1 shared Claudio Novella-RauselliD· 1 shared Gangqi WangiD· 1 shared Marleen E JacobsiD· 1 shared Nina OgrinciD· 1 shared Rosalie G. J. RietjensiD· 1 shared Sébastien J. DumasiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperBioinformatics

Ahmed Essam MahfouzORCID

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1 paper

Recent·Most cited

Image-guided alignment of consecutive multi-modal tissue slides

Benedetta Manzato, Claudio Novella-Rausell, Gangqi Wang, Nina Ogrinc, Rosalie G. J. Rietjens, Marleen E Jacobs, Christos Botos, Sébastien J. Dumas, Ton J. Rabelink, Ahmed Essam Mahfouz

COAST aligns consecutive tissue sections using only spatial images, enabling unified multi-modal molecular data analysis without molecular markers or annotations.

Cell Reports Methods · Sep 1, 2026Peer-reviewedBioinformatics