Lysosomal lipidomics identifies glycosylated bis(monoacylglycero)phosphate as a novel biomarker of mutant GBA1
Cindy Lin, Miharu Iguchi, Jacob Oh, Aleksandra Levina, Zhijun Zhu, Jian Xiong, Wentao Dong, Hisham N. Alsohybe, Nicole Briceno, Kelly Chau, Alina Isakova, Yu Chen, Ellen Sidransky, Monther Abu-Remaileh
This study identifies HexBMP(22:6_22:6) as a novel biomarker for mutant GBA1 using lysosomal profiling in mice and human samples.
bioRxiv · Oct 15, 2026 · PreprintNeuroscience