Genotype-predicted drug response phenotypes and their co-occurrence with dispensed medicines among 738,531 participants in the UK Our Future Health study
Christopher T. Rentsch, Krishnan Bhaskaran, Mirko Pavicic, Helen R. Warren, Julian Matthewman, Eleanor V.H. Barry, Imran Rafi, Judith Hayward, Clare Gerada, Anoop S.V. Shah, Patricia B. Munroe, Matt J. Silver, Munir Pirmohamed
The paper assesses the co-occurrence of actionable pharmacogenomic phenotypes with dispensed medicines in 738,531 UK participants, finding 36.8% had gene-matched medications.
medRxiv · Aug 12, 2026 · PreprintGenetic & Genomic Medicine