Matt J. Silver

The paper assesses the co-occurrence of actionable pharmacogenomic phenotypes with dispensed medicines in 738,531 UK participants, finding 36.8% had gene-matched medications.

The paper identifies systemic epigenetic variants linked to periconceptional environments in human fetal development, finding more variants in Black Americans and associations with cancer and neurodevelopment.

The paper identifies DNA methylation marks linked to body composition traits in children from India and The Gambia using an epigenome-wide association study.

The paper links KZFP-mediated DNA methylation of a primate-specific transposon to type 1 diabetes risk through genetic and epigenetic analyses.

This study identifies DNA methylation at the SOCS3 gene as a factor influencing child height in low and middle-income countries, with a causal effect confirmed by Mendelian randomization.

The paper identifies hypervariable DNA methylation sites across multiple tissues and ethnicities, showing they are influenced by environmental factors and established early in human development.

The paper identifies CpGs in the early human embryo methylome associated with season of conception, showing environmental influences on DNA methylation.