Phenotypic Screening Identifies Small-Molecule Inhibitors with Distinct Activities across the BK Polyomavirus Life Cycle
Clara Husser, Hannes G. Roggenkamp, Emma Kraus, Patrick Blümke, Sanamjeet Virdi, Claudia Schmidt, Jessica Rückert, Thomas Friedrich Schulz, Adam T. Grundhoff, Nicole Fischer
This study identifies small-molecule inhibitors of BK polyomavirus infection through phenotypic screening, revealing compounds with distinct antiviral mechanisms and cellular effects.
bioRxiv · Aug 20, 2026 · PreprintMicrobiology