Supramammillary projections to the lateral preoptic area drive dopamine release and active behavior
Satoshi Ikemoto, Yosuke Arima, Zengyou Ye, Coleman Calva, Xia Min, John Gibbons, Jorge Mendoza, Beyonce Getachew, Sarah A. Johnson, Marziyeh Belal
The paper identifies the SuM[->]LPO pathway as a circuit that modulates dopamine release and active behavior through interactions with mesolimbic dopamine signaling.
bioRxiv · Sep 7, 2026 · PreprintNeuroscience