Remodeling-mediated changes in left ventricular mechanics under settings of chronic pressure overload and exercise
Francesco K. Yigamawano, Ricky Ruiz, Conner E. Johnson, Alexander Barnette, Lisa Freeburg, Kurt G. Barringhaus, Francis G. Spinale, Tarek M. Shazly
This study uses speckle-tracking echocardiography to monitor LV remodeling in porcine models of pressure overload, exercise, and their combination, finding divergent effects on myocardial and chamber stiffness.
Journal of Biomechanical Engineering · Apr 15, 2026Peer-reviewedBioengineering