Author

Craig Dobbins

University of Washington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:protein design· 2 Approach:deep learning· 1 Organism:human· 1 Organism:mouse· 1 Assay:protein sequence· 1 Assay:protein structure· 1

Frequent Co-Authors

Brian CoventryiD· 2 shared Maggie AhlrichsiD· 2 shared Neil P. KingiD· 2 shared A G MurrayiD· 1 shared Abigail E. BurtneriD· 1 shared Adam M. Chazin-GrayiD· 1 shared Adian Valdez· 1 shared Adri Tran-Pearson· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersBiochemistry

Brian CoventryORCID

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Author profile →

3 papers

Recent·Most cited

De novo design of protein minibinder agonists of TLR3

Chloe S. Adams, Hyojin Kim, Abigail E. Burtner, Dong Sun Lee, Craig Dobbins, Cameron Criswell, Brian Coventry, Adri Tran-Pearson, Ho Min Kim, Neil P. King

This study designs protein minibinders that act as agonists for TLR3, showing nanomolar binding and biological activity in cell lines.

Nature Communications · Jan 31, 2025Peer-reviewedBiochemistry

Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV

Cara W. Chao, Kaitlin R. Sprouse, Marcos C. Miranda, Nicholas J. Catanzaro, Miranda L. Hubbard, Amin Addetia, Cameron Stewart, Jack T. Brown, Annie M. Dosey, Adian Valdez, Rashmi Ravichandran, Grace G. Hendricks, Maggie Ahlrichs, Craig Dobbins, Alexis Hand, , Neil P. King

This study develops MERS-CoV vaccines using a protein nanoparticle platform, showing they induce strong neutralizing antibodies and protect mice against MERS-CoV challenge.

Cell Reports · Dec 1, 2024Peer-reviewedImmunology

Designed Endocytosis-Triggering Proteins mediate Targeted Degradation and amplify signaling

Buwei Huang, Mohamad H. Abedi, Green Ahn, Brian Coventry, Isaac Sappington, Rong Wang, Thomas Schlichthaerle, Jason Z. Zhang, Yujia Wang, Inna Goreshnik, Ching Wen Chiu, Adam M. Chazin-Gray, Sidney Chan, Stacey Gerben, A G Murray, , David A. Baker

The paper designs EndoTags to trigger endocytosis and degradation of target proteins, enabling tissue-specific targeting and therapeutic applications.

bioRxiv · Aug 19, 2023 · PreprintSynthetic Biology