Chemi-Proteome Language Attention Network Empowers Fragment-Based Ligand Interactome and Binding Sites Discovery with Evidence
Bin Liao, Jixiao He, Mingzhu Zhao, Xiaozhen Cui, Cui Yunxia, Chuanqiao Dong, Hongyan Sun, Liang Zhang, Jian Zhang
C-PLANK improves ligand-protein interaction prediction by integrating cellular context and fragment-based chemoproteomics data, outperforming existing methods and identifying novel ligands.
bioRxiv · Aug 30, 2026 · PreprintBioinformatics