Cold exposure induces the constitutively active thermogenic receptor, GPR3, via ERRα and ERRγ
Olivia Sveidahl Johansen, Rebecca L. McIntyre, Janane F. Rahbani, Qiaoqiao Zhang, Charlotte Scholtes, Damien Lagarde, Cyrielle Billon, Isabelle Côté, Maria Delgado-Martin, David Tandio, Astrid Linde Basse, Elodie Eury, Anastasia Kralli, Thomas P. Burris, Vincent Giguère, , Zachary Gerhart‐Hines
The paper identifies ERRα and ERRγ as regulators of cold-induced GPR3 expression in adipocytes, showing their role in thermogenic energy expenditure.
Molecular Metabolism · Oct 30, 2025Peer-reviewedMolecular Biology