Ubiquitylation of nucleic acids by DELTEX ubiquitin E3 ligase DTX3L
K. Zhu, C. Chatrin, M. Suskiewicz, V. Aucagne, D. Ahel, I. Ahel
This study shows that nucleic acids can be ubiquitylated by DTX3L, an E3 ligase, and this modification is reversible by DUBs like USP2 and SARS-CoV-2 PLpro.
bioRxiv · Apr 19, 2024Biochemistry