Lifelong tissue memory relies on spatially organised dedicated progenitors located distally from the injury
C. L. Levron, M. Watanabe, V. Proserpio, G. Piacenti, A. Lauria, S. Kaltenbach, T. Nohara, F. Anselmi, C. Duval, D. Donna, D. Baev, K. Natsuga, T. Hagai, S. Oliviero, G. Donati
The paper shows that wound repair leads to the formation of spatially organized memory progenitors that enhance future wound healing but also increase tumorigenesis risk.
bioRxiv · Feb 2, 2023Cell Biology