Tyrosine-Derived Polycarbonate Nerve Guidance Tubes Elicit Pro-Regenerative Extracellular Matrix Deposition When Used to Bridge Segmental Nerve Defects in Swine
J. C. Burrell, D. Bhatnagar, D. P. Brown, N. S. Murthy, J. Dutton, F. A. Laimo, Z. Ali, J. M. Rosen, H. M. Kaplan, J. Kohn, D. K. Cullen
This study evaluates tyrosine-derived polycarbonate nerve guidance tubes in swine, showing they promote pro-regenerative extracellular matrix deposition and Schwann cell infiltration compared to collagen-based tubes.
bioRxiv · Jan 11, 2020Bioengineering