Small-Molecule In Vitro Inhibitors of the Coronavirus Spike - ACE2 Protein-Protein Interaction as Blockers of Viral Attachment and Entry for SARS-CoV-2
D. Bojadzic, O. Alcazar, J. Chen, P. Buchwald
The paper identifies small-molecule inhibitors of the SARS-CoV-2 spike-ACE2 interaction, showing they block viral entry with low micromolar activity.
bioRxiv · Oct 22, 2020Pharmacology & Toxicology