Isomeric O-methyl cannabidiolquinones with dual BACH1/NRF2 activity
L. Casares, J. D. Unciti, M. E. Prados, D. Caprioglio, M. Higgins, G. Apendino, A. T. Dinkova-Kostova, E. Munoz, L. de la Vega
The paper develops a CBD derivative with dual BACH1 inhibition and NRF2 activation, showing neuroprotection in Huntington's disease cell models.
bioRxiv · Jun 16, 2020Cell Biology