Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
7 papers
Recent·Most cited
H. Yu, H. Nishio, J. Barbi, M. Mitchell-Flack, P. D. A. Vignali, Y. Zheng, A. Lebid, K.-Y. Chang, J. Fu, M. Higgins, C.-T. Huang, X. Zhang, Z. Li, L. Blosser, A. Tam, , D. M. Pardoll
This study shows that neuritin modulates T cell electrical and metabolic states, influencing immune tolerance and immunity.
bioRxiv · Jan 31, 2024Immunology
F. Colomb, A. Ogunkanbi, A. Jamwal, B. Dong, R. M. Maizels, C. A. Finney, J. D. Wasmuth, M. Higgins, H. McSorley
The paper identifies three HpARI family members in H. polygyrus bakeri, showing they have distinct effects on IL-33-dependent Type 2 immune responses.
bioRxiv · Oct 9, 2023Immunology
L. Casares, R. Moreno, M. Higgins, S. D. Naidu, G. Neill, L. Cassin, A. E. Kiib, E. B. Svenningsen, T. Honda, T. B. Poulsen, A. T. Dinkova-Kostova, D. Olagnier, L. de la Vega
This study identifies CDDO-derivatives as BACH1 inhibitors, explaining their higher potency as HMOX1 inducers compared to CDDO.
bioRxiv · Oct 29, 2021 · PreprintCell Biology
D. G. Ryan, E. V. Knatko, A. Casey, J. L. Hukelmann, A. J. Brenes, S. Dayalan Naidu, M. Higgins, L. Tronci, E. Nikitopoulou, L. A. O'Neill, A. I. Lamond, A. Y. Abramov, D. A. Cantrell, M. P. Murphy, A. T. Dinkova-Kostova
This study shows Nrf2 regulates macrophage metabolism, redox balance, and inflammatory responses, with 4-OI modulating these effects through Nrf2.
bioRxiv · Aug 13, 2021 · PreprintImmunology
I. Campeotto, F. Galaway, S. Mehmood, L. Barfod, D. Quinkert, V. Kotraiah, T. W. Phares, K. E. Wright, A. P. Snijders, S. J. Draper, M. Higgins, G. J. Wright
The paper determines the structure of the RH5-binding region of P113 and identifies the binding site, providing insights for malaria vaccine development.
mBio · Oct 27, 2020Peer-reviewedMicrobiology
D. E. Webster, M. Tummalacherla, M. Higgins, D. Wing, E. Ashley, V. E. Kelly, M. V. McConnell, E. D. Muse, J. Olgin, L. Mangravite, J. Godino, M. Kellen, L. Omberg
This paper develops and validates a smartphone-based method to estimate VO2max using a 3-minute step test, showing high reliability and minimal bias across diverse populations.
bioRxiv · Jul 2, 2020 · PreprintBioengineering
L. Casares, J. D. Unciti, M. E. Prados, D. Caprioglio, M. Higgins, G. Apendino, A. T. Dinkova-Kostova, E. Munoz, L. de la Vega
The paper develops a CBD derivative with dual BACH1 inhibition and NRF2 activation, showing neuroprotection in Huntington's disease cell models.
bioRxiv · Jun 16, 2020Cell Biology