Author

D. Fleifel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:proteomics· 1

Frequent Co-Authors

B. L. Mouery· 2 shared J. G. Cook· 2 shared A. M. House· 1 shared A. N. Littlejohn· 1 shared A. Walens· 1 shared B. Ma· 1 shared C. A. Mills· 1 shared D. Dominguez· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

B. L. Mouery

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

APC/C prevents non-canonical order of cyclin/CDK activity to maintain CDK4/6 inhibitor-induced arrest

B. L. Mouery, E. M. Baker, C. A. Mills, L. E. Herring, D. Fleifel, J. G. Cook

This paper shows APC/C activity is essential to maintain CDK4/6 inhibitor-induced arrest by preventing premature S phase entry through degradation of cyclin A.

bioRxiv · Nov 9, 2023 · PreprintCell Biology

Quantitative Profiling of Adaptation to Cyclin E Overproduction

J. C. Limas, A. N. Littlejohn, A. M. House, K. M. Kedziora, B. L. Mouery, B. Ma, D. Fleifel, A. Walens, M. M. Aleman, D. Dominguez, J. G. Cook

This study examines how mammalian cells adapt to chronic cyclin E overproduction, revealing that adaptation involves downregulation of G1-regulated genes and partial resistance to replication stress.

bioRxiv · Jul 26, 2021Cell Biology