Rapid degradation and 3D CLEM of condensin reveal chromatin compaction uncoupled from chromosome architecture in mitosis
K. Samejima, D. G. Booth, H. Ogawa, J. R. Paulson, L. Xie, C. A. Watson, M. Platani, M. T. Kanemaki, W. C. Earnshaw
This study shows that condensin is essential for anaphase chromosome segregation and normal chromosome architecture formation, but not for chromatin compaction during mitosis.
bioRxiv · Aug 9, 2017Cell Biology