Condensin reorganizes centromeric chromatin during mitotic entry into a bipartite structure stabilized by cohesin
C. Sacristan, K. Samejima, L. Andrade Ruiz, M. L. A. Lambers, A. Buckle, C. A. Brackley, D. Robertson, T. Hori, S. Webb, T. Fukagawa, N. Gilbert, D. Marenduzzo, W. C. Earnshaw, G. J. P. L. Kops
This study shows vertebrate centromeres form a bipartite structure during mitosis, stabilized by condensin and linked by cohesin, which prevents merotelic attachments and chromosomal instability.
bioRxiv · Aug 1, 2022 · PreprintCell Biology