Acute-phase CD4+ T cell responses targeting invariant viral regions are associated with control of live-attenuated simian immunodeficiency virus
M. S. Sutton, A. Ellis-Connell, R. V. Moriarty, A. J. Balgeman, D. Gellerup, G. L. Barry, A. M. Weiler, T. C. Friedrich, S. L. O'Connor
This study shows that CD4+ T cell responses targeting invariant viral regions in MCMs without protective MHC alleles correlate with lower viral load during SIV infection.
bioRxiv · May 13, 2018Immunology