The transcriptional hallmarks of intra-tumor heterogeneity across a thousand tumors
A. Gavish, M. Tyler, D. Simkin, D. Kovarsky, L. N. Gonzalez Castro, D. Halder, R. Chanoch-Myers, J. Laffy, M. Mints, A. R. Greenwald, A. Weider, R. Tal, A. Spitzer, T. Hara, A. Tirosh, , I. Tirosh
This study integrates single-cell RNA-seq data from 1,163 tumors across 24 types to identify 41 consensus transcriptional programs and 11 hallmarks of intra-tumor heterogeneity.
bioRxiv · Dec 19, 2021 · PreprintCancer Biology