Regulation of the 20S proteasome by a novel family of inhibitory proteins
M. A. Olshina, F. Kumar-Deshmukh, G. Arkind, I. Fainer, M. Taranavsky, D. Hayat, S. Ben-Dor, G. Ben-Nissqan, M. Sharon
The paper identifies a family of 20S proteasome regulators, CCRs, that modulate proteasome activity through a feed-forward loop involving Nrf2 and oxidative stress response.
bioRxiv · Apr 24, 2019Biochemistry