Cancer-associated fibroblasts exert a pro-angiogenic activity in Merkel cell carcinoma
S. Albertini, L. Martuscelli, C. Borgogna, S. Virdi, D. Indenbirken, I. Lo Cigno, G. Griffante, F. Calati, R. L. Boldorini, N. Fischer, M. Gariglio
This study identifies cancer-associated fibroblasts (CAFs) in Merkel cell carcinoma (MCC) as pro-angiogenic and shows their role in tumor growth and metastasis through the APA/Ang II-III/AT1R axis.
bioRxiv · Jul 30, 2021Cancer Biology