Author

N. Fischer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Grundhoff· 2 shared M. Aepfelbacher· 2 shared A. Bousvaros· 1 shared A. Carstens· 1 shared A. Chari· 1 shared A. Levine· 1 shared A.-S. Schroeder· 1 shared B. Yerushalmi· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

A. Grundhoff

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Yersinia remodels epigenetic histone modifications in human macrophages

I. Bekere, J. Huang, M. Schnapp, M. Rudolph, L. Berneking, K. Ruckdeschel, A. Grundhoff, T. Günther, N. Fischer, M. Aepfelbacher

This study shows Yersinia enterocolitica modulates histone modifications in human macrophages to alter gene expression related to immune response and metabolism.

bioRxiv · Sep 7, 2021Microbiology

Cancer-associated fibroblasts exert a pro-angiogenic activity in Merkel cell carcinoma

S. Albertini, L. Martuscelli, C. Borgogna, S. Virdi, D. Indenbirken, I. Lo Cigno, G. Griffante, F. Calati, R. L. Boldorini, N. Fischer, M. Gariglio

This study identifies cancer-associated fibroblasts (CAFs) in Merkel cell carcinoma (MCC) as pro-angiogenic and shows their role in tumor growth and metastasis through the APA/Ang II-III/AT1R axis.

bioRxiv · Jul 30, 2021Cancer Biology

SARS-CoV-2 infects carotid arteries: implications for vascular disease and organ injury in COVID-19

S. Pfefferle, T. Guenther, V. Puelles, F. Heinrich, D. Noerz, M. Czech-Sioli, A. Carstens, S. Krasemann, M. Wong, L. Oestereich, T. Magnus, L. Allweiss, C. Edler, A.-S. Schroeder, M. Dandri, , N. Fischer

The paper investigates SARS-CoV-2 infection in carotid arteries of COVID-19 patients using genomic, virologic, histochemical, and transcriptomic analyses, showing productive infection and vascular modulation.

bioRxiv · Oct 10, 2020 · PreprintMicrobiology

Breaking the next Cryo-EM resolution barrier - Atomic resolution determination of proteins!

K. M. Yip, N. Fischer, E. Paknia, A. Chari, H. Stark

This paper reports a 1.25 Å resolution cryo-EM structure of apoferritin, achieving atomic-level detail and improving density map quality for drug design.

bioRxiv · May 21, 2020 · PreprintBiophysics

Treatment-Specific Composition of Gut Microbiota Is Associated with Disease Remission in a Pediatric Crohn’s Disease Cohort

D. Sprockett, N. Fischer, R. S. Boneh, D. Turner, J. Kierkus, M. Sladek, J. Escher, E. Wine, B. Yerushalmi, J. A. Dias, R. Shaoul, M. Kori, S. Snapper, S. Holmes, A. Bousvaros, , D. A. Relman

This study examines how gut microbiota changes with metronidazole and metronidazole plus azithromycin treatments in pediatric Crohn’s disease and finds that microbiota profiles can predict disease remission.

bioRxiv · May 19, 2019Microbiology