SICKO: Systematic Imaging of Caenorhabditis Killing Organisms
L. S. Espejo, S. Freitas, V. Hofschneider, L. Chang, A. Antenor, J. Balsa, A. Haskins, D. DeNicola, H. Dang, S. Hamming, D. Kelser, G. L. Sutphin
SICKO enables longitudinal tracking of microbial colonization and host survival in C. elegans, revealing that gut colonization by E. coli or Pseudomonas aeruginosa shortens lifespan and that pmk-1-deficient animals are more susceptible.
bioRxiv · Feb 17, 2023 · PreprintImmunology