Biologically-derived neoproteoglycans for profiling protein-glycosaminoglycan interactions
R. N. Porell, J. L. Follmar, S. C. Purcell, B. Timm, L. K. Laubach, D. Kozirovskiy, B. E. Thacker, C. A. Glass, P. L. S. M. Gordts, K. Godula
This paper introduces neoproteoglycans (neoPGs) as biologically-derived probes to study protein-glycosaminoglycan interactions, enabling real-time monitoring and analysis of ligand binding and enzyme specificity.
bioRxiv · Mar 4, 2022Biochemistry