Author

D. L. Durden

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. Acharya· 1 shared G. A. Morales· 1 shared K. B. Challagundla· 1 shared K. Pandey· 1 shared K. R. Vann· 1 shared M. Thurman· 1 shared S. N. Byrareddy· 1 shared T. G. Kutateladze· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Acharya

Mutual co-authors in cluster

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1 paper

Recent·Most cited

Blockade of SARS-CoV-2 infection in-vitro by highly potent PI3K-α/mTOR/BRD4 inhibitor

A. Acharya, K. Pandey, M. Thurman, K. B. Challagundla, K. R. Vann, T. G. Kutateladze, G. A. Morales, D. L. Durden, S. N. Byrareddy

The paper demonstrates that SF2523, a PI3K-α/mTOR/BRD4 inhibitor, effectively blocks SARS-CoV-2 replication in vitro with an IC50 of 1.5 μM and shows synergy with remdesivir.

bioRxiv · Mar 2, 2021 · PreprintPharmacology & Toxicology