Bacteriophage-derived dsRNA exerts anti-SARS-CoV-2 activity in vitro and in Golden Syrian hamsters in vivo
K. Vaivode, I. Verhovcova, D. Skrastina, R. Petrovska, M. Kreismane, D. Lapse, D. Rubene, Z. Kalnina, D. Pjanova
This study demonstrates that bacteriophage-derived dsRNA (Larifan) inhibits SARS-CoV-2 replication in vitro and reduces viral load in infected hamsters, with improved lung histopathology.
bioRxiv · Jan 22, 2022Microbiology