Endothelial stiffening induced by CD36-mediated lipid uptake leads to endothelial barrier disruption and contributes to atherosclerotic lesions
V. Aguilar, E. Le Master, A. Paul, S. J. Ahn, D. Lazarko, M. Febbraio, J. C. Lee, I. Levitan
This study shows that CD36-mediated lipid uptake causes endothelial stiffening, leading to barrier disruption and atherosclerosis in mouse models, with sex-dependent effects.
bioRxiv · Nov 8, 2023Cell Biology