Author

D. Lefaudeux

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Hoffmann· 1 shared A. S. Meyer· 1 shared A. Zuniga Munoz· 1 shared C. Wilder· 1 shared K. Kishimoto· 1 shared M. A. Nguyen· 1 shared Q. J. Cheng· 1 shared R. Mathenge· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperImmunology

A. Hoffmann

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1 paper

Recent·Most cited

A stimulus-contingent positive feedback loop enables IFN-β dose-dependent activation of pro-inflammatory genes

C. Wilder, D. Lefaudeux, R. Mathenge, K. Kishimoto, A. Zuniga Munoz, M. A. Nguyen, A. S. Meyer, Q. J. Cheng, A. Hoffmann

The paper shows high-dose IFN-β activates a pro-inflammatory gene program through a stimulus-contingent positive feedback loop in ISGF3, unlike IFN-λ3.

bioRxiv · Aug 11, 2022Immunology