Author

D. Lynch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Approach:biophysical modeling· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

A. Acharya· 2 shared A. Pavlova· 2 shared J. Gumbart· 2 shared Y. T. Pang· 2 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersBiophysics

A. Acharya

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2 papers

Recent·Most cited

SARS-CoV-2 spike opening dynamics and energetics reveal the individual roles of glycans and their collective impact

Y. T. Pang, A. Acharya, D. Lynch, A. Pavlova, J. Gumbart

This study uses molecular dynamics simulations to analyze how glycans affect the opening dynamics and energetics of the SARS-CoV-2 spike protein, revealing their individual and collective roles in stabilizing the closed and open states.

bioRxiv · Aug 12, 2021Biophysics

ACE2 glycans preferentially interact with the RBD of SARS-CoV-2 over SARS-CoV

A. Acharya, D. Lynch, A. Pavlova, Y. T. Pang, J. Gumbart

The paper identifies differences in ACE2 glycan interactions with SARS-CoV-2 and SARS-CoV RBDs, showing N322 enhances SARS-CoV-2 binding while N90 may provide protection.

bioRxiv · Apr 29, 2021Biophysics