In Vitro Inhibition of SARS-CoV-2 Infection by Bromhexine hydrochloride
R. Martins, I. Ferreira, D. M. Jorge, L. Almeida, J. d. P. Souza, M. C. Pontelli, I. A. Castro, T. Melquiades, R. M. Mendes Viana, D. S. Zamboni, P. Marcato, E. Arruda
This study shows bromhexine hydrochloride inhibits SARS-CoV-2 infection in vitro by targeting TMPRSS2, reducing viral entry and progeny without direct virucidal activity.
bioRxiv · Dec 23, 2022 · PreprintPharmacology & Toxicology