E. Arruda

Comprehensive Molecular Epidemiology of Influenza Viruses in Brazil: Insights from a Nationwide Analysis

This study analyzes the molecular epidemiology of Influenza A and B viruses in Brazil from 2021 to 2023, revealing lineage dominance patterns and mutations that may impact vaccine efficacy.

Differential action modes of Neutrophil Extracellular Trap-targeted drugs define T cell responses in SARS-CoV-2 infection.

This study compares how two NET-targeting drugs, rhDNase and GSK484, affect T cell responses in SARS-CoV-2 infection, showing differing impacts on adaptive immunity.

In Vitro Inhibition of SARS-CoV-2 Infection by Bromhexine hydrochloride

This study shows bromhexine hydrochloride inhibits SARS-CoV-2 infection in vitro by targeting TMPRSS2, reducing viral entry and progeny without direct virucidal activity.

Ultrasound inhibits SARS-CoV-2 infectivity in vitro

This study shows ultrasound can reduce SARS-CoV-2 infectivity in vitro without causing heat or cavitation.

Targeting C5aR1 signaling reduced neutrophil extracellular traps and ameliorates COVID-19 pathology

This study shows that inhibiting C5aR1 signaling reduces neutrophil extracellular traps and improves lung pathology in COVID-19.

Targeting Neutrophils Extracellular Traps (NETs) reduces multiple organ injury in a COVID-19 mouse model

This study shows that DNase I treatment reduces NETs and organ injury in a COVID-19 mouse model.

The replication of the human respiratory syncytial virus in a T cell line has multiple ineffective steps

This study shows that HRSV infection of CD4+ T cells is inefficient compared to epithelial cells, with reduced fusion, lower protein production, and altered viral trafficking.

Infection of human lymphomononuclear cells by SARS-CoV-2

This study investigates SARS-CoV-2 infection of human lymphomononuclear cells in vitro and in vivo, finding that monocytes, B cells, and T cells are susceptible to infection and viral replication.