Epistatic interactions within the influenza virus polymerase complex mediate mutagen resistance and replication fidelity
M. D. Pauly, D. M. Lyons, A. S. Lauring
The paper identifies mutagen-resistant mutations in the influenza virus polymerase complex and shows how epistatic interactions between mutations affect replication fidelity and drug resistance.
bioRxiv · Apr 27, 2017Microbiology