Author

D. Moi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Research Focus:phylogenetics / evolution· 2 Approach:statistical model· 2 Organism:Arabidopsis· 1 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. Dessimoz· 3 shared B. Podbilewicz· 2 shared C. Valansi· 2 shared H. Romero· 2 shared M. Grana· 2 shared P. S. Aguilar· 2 shared R. Benton· 2 shared A. R. Wilson· 1 shared

Activity by Year

2016-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersEvolutionary Biology

C. Dessimoz

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Author profile →

5 papers

Recent·Most cited

Remote homolog detection places insect chemoreceptors in a cryptic protein superfamily spanning the tree of life

N. J. Himmel, D. Moi, R. Benton

The paper identifies thousands of new 7-transmembrane ion channel homologs across diverse taxa using a pipeline combining structure-based methods and graph analysis, revealing a cryptic superfamily with deep evolutionary origins.

bioRxiv · Aug 30, 2023Evolutionary Biology

Discovery of archaeal Fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins

D. Moi, S. Nishio, X. Li, C. Valansi, M. Langleib, N. G. Brukman, K. Flyak, C. Dessimoz, D. de Sanctis, K. Tunyasuvunakool, J. Jumper, M. Grana, H. Romero, P. S. Aguilar, L. Jovine, B. Podbilewicz

The paper identifies archaeal proteins homologous to eukaryotic gamete fusion proteins and shows they can mediate cell fusion.

bioRxiv · Oct 13, 2021Evolutionary Biology

A putative origin of insect chemosensory receptors in the last common eukaryotic ancestor

R. Benton, C. Dessimoz, D. Moi

The paper identifies GRL proteins in unicellular eukaryotes and uses structure predictions to suggest their origin in the last common eukaryotic ancestor.

bioRxiv · Aug 24, 2020Evolutionary Biology

Protein citrullination was introduced into animals by horizontal gene transfer from cyanobacteria

T. F. Cummings, K. Gori, L. Sanchez-Pulido, G. Gavriilidis, D. Moi, A. R. Wilson, E. P. Murchison, C. Dessimoz, C. Ponting, M. A. Christophorou

This study identifies horizontal gene transfer of citrullinating enzymes from cyanobacteria to animals, revealing an ancient origin of a key post-translational modification.

bioRxiv · Jun 13, 2020Evolutionary Biology

Arabidopsis HAP2/GCS1 is a gamete fusion protein homologous to somatic and viral fusogens

C. Valansi, D. Moi, E. Leikina, E. Matveev, M. Grana, L. V. Chernomordik, H. Romero, P. S. Aguilar, B. Podbilewicz

This paper shows that Arabidopsis HAP2/GCS1 promotes cell-cell fusion and virus-cell fusion, sharing a mechanism with somatic fusogens and viruses, and proposes a new superfamily called FUSEXINS.

bioRxiv · Dec 31, 2016Cell Biology