C. Dessimoz

Matreex: compact and interactive visualisation for scalable studies of large gene families

Matreex provides a scalable visualization tool for large gene families by using phylogenetic profiles to minimize information loss during subtree collapsing.

Control of PHYTOCHROME KINASE SUBSTRATE subcellular localization and biological activity by protein S-acylation

This study identifies S-acylation of PKS4 motif C as critical for its plasma membrane association and biological activity in light-regulated growth responses.

Protein length distribution is remarkably consistent across Life

The paper compares protein length distribution across 2,326 species and finds it is more consistent than expected, suggesting universal purifying selection.

Discovery of archaeal Fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins

The paper identifies archaeal proteins homologous to eukaryotic gamete fusion proteins and shows they can mediate cell fusion.

A putative origin of insect chemosensory receptors in the last common eukaryotic ancestor

The paper identifies GRL proteins in unicellular eukaryotes and uses structure predictions to suggest their origin in the last common eukaryotic ancestor.

Protein citrullination was introduced into animals by horizontal gene transfer from cyanobacteria

This study identifies horizontal gene transfer of citrullinating enzymes from cyanobacteria to animals, revealing an ancient origin of a key post-translational modification.

The phylogenetic range of bacterial and viral pathogens of vertebrates

The paper compiles a large host-pathogen association database and analyzes factors influencing host range and zoonotic potential across bacteria and viruses.