High-Risk Human Papillomavirus E7 Alters Host DNA Methylome And Represses HLA-E Expression In Human Keratinocytes
L. Cicchini, R. Z. Blumhagen, J. A. Westrich, M. E. Meyers, C. J. Warren, C. Siska, D. Raben, K. J. Kechris, D. Pyeon
This study shows high-risk HPV E7 induces DNA methylation changes that repress HLA-E expression in keratinocytes, potentially aiding immune evasion.
bioRxiv · May 1, 2017Immunology