Low T cell diversity is associated with poor outcome in bladder cancer: a comprehensive longitudinal analysis of the T cell receptor repertoire
A. Kjaer, N. Kristjansdottir, R. I. Juul, I. Nordentoft, K. Birkenkamp-Demtroder, J. Ahrenfeldt, T. Strandgaard, D. Radif, D. Hodgson, C. Abbosh, H. J. Aerts, M. Agerbaek, J. B. Jensen, N. J. Birkbak, L. Dyrskjot
This study shows that low T cell receptor diversity in bladder cancer patients is linked to poor outcomes and identifies TCR diversity as a potential biomarker for treatment.
bioRxiv · May 30, 2024 · PreprintCancer Biology