Author

C. Abbosh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Droop· 1 shared A. J. Davies· 1 shared A. Kjaer· 1 shared A. Patel· 1 shared B. Da Silva· 1 shared D. Hodgson· 1 shared D. Radif· 1 shared E. Chuntharpursat-Bon· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Droop

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Author profile →

2 papers

Recent·Most cited

Low T cell diversity is associated with poor outcome in bladder cancer: a comprehensive longitudinal analysis of the T cell receptor repertoire

A. Kjaer, N. Kristjansdottir, R. I. Juul, I. Nordentoft, K. Birkenkamp-Demtroder, J. Ahrenfeldt, T. Strandgaard, D. Radif, D. Hodgson, C. Abbosh, H. J. Aerts, M. Agerbaek, J. B. Jensen, N. J. Birkbak, L. Dyrskjot

This study shows that low T cell receptor diversity in bladder cancer patients is linked to poor outcomes and identifies TCR diversity as a potential biomarker for treatment.

bioRxiv · May 30, 2024 · PreprintCancer Biology

The small molecule KHS101 induces bioenergetic dysfunction in glioblastoma cells through inhibition of mitochondrial HSPD1

E. S. Polson, V. B. Kuchler, C. Abbosh, E. M. Ross, R. K. Mathew, H. A. Beard, E. Chuntharpursat-Bon, J. Williams, B. Da Silva, H. Shao, A. Patel, A. J. Davies, A. Droop, H. B. S. Griffiths, P. Chumas, , H. Wurdak

The paper shows KHS101 inhibits HSPD1 in glioblastoma cells, causing metabolic dysfunction and tumor growth reduction without affecting normal cells.

bioRxiv · Oct 18, 2017Cancer Biology