A Global Transcriptional Atlas of the Effect of Sleep Deprivation in the Mouse Frontal Cortex
K. Ford, E. Zuin, D. Righelli, E. Medina, H. Schoch, K. Singletary, C. Muheim, M. G. Frank, S. Hicks, D. Risso, L. Peixoto
This study presents a global transcriptional atlas of sleep deprivation effects in mouse frontal cortex using bulk and single-nuclear RNA sequencing, showing widespread transcriptional repression and isoform switching in glutamatergic neurons.
bioRxiv · Nov 28, 2023 · PreprintNeuroscience