Author

D. Shanley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Approach:deep learning· 1 Assay:DNA methylation· 1 Organism:human· 1 Research Focus:variant calling· 1

Frequent Co-Authors

D. C. Green· 1 shared E. G. Canty-Laird· 1 shared H. O'Keefe· 1 shared J. Henstock· 1 shared J. Wordsworth· 1 shared K. Gutvik· 1 shared L. Reynard· 1 shared M. Peffers· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

D. C. Green

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2 papers

Recent·Most cited

MskAge - An Epigenetic Biomarker of Musculoskeletal Age Derived from a Genetic Algorithm Islands Model

D. C. Green, L. Reynard, J. Henstock, S. Reppe, K. Gutvik, M. Peffers, D. Shanley, P. D. Clegg, E. G. Canty-Laird

This paper develops MskAge, an epigenetic biomarker for musculoskeletal age, showing higher accuracy than existing clocks in tracking in vitro ageing and reprogramming.

bioRxiv · May 4, 2023Cell Biology

The damage-independent evolution of ageing by selective destruction

J. Wordsworth, D. Shanley, H. O'Keefe, P. Clark

This paper proposes an alternative theory to disposable soma theory, suggesting ageing arises from selective destruction of fast-growing cells, leading to metabolic slowdown and increased mortality.

bioRxiv · May 3, 2022Evolutionary Biology