Directing iPSC Differentiation into iTenocytes using Combined Scleraxis Overexpression and Cyclic Loading
A. Papalamprou, V. Yu, A. Chen, T. Stefanovic, G. Kaneda, K. Salehi, C. Castaneda, A. Gertych, J. D. Glaeser, D. Sheyn
This study differentiates iPSC-derived MSCs into tenocytes using Scleraxis overexpression and mechanical stretch, showing improved tendon marker expression and ECM alignment compared to BM-MSCs.
bioRxiv · Nov 23, 2021Cell Biology