Seven amino acid types suffice to reconstruct the core fold of RNA polymerase
S. Yagi, A. K. Padhi, J. Vucinic, S. Barbe, T. Schiex, R. Nakagawa, D. Simoncini, K. Y. J. Zhang, S. Tagami
The paper reconstructs the DPBB fold using only seven amino acid types, suggesting it could have emerged with the early genetic code.
bioRxiv · Feb 22, 2021Biochemistry