D. Skotnicka

During heat stress in Myxococcus xanthus, the CdbS PilZ domain protein, along with two PilZ-DnaK chaperones, perturbs chromosome organization and accelerates cell death

The paper shows that in Myxococcus xanthus, CdbA regulates CdbS levels to maintain chromosome organization, and its depletion leads to CdbS over-accumulation, causing cell death, especially under heat stress.

Three PilZ domain proteins, PlpA, PixA and PixB, have distinct functions in regulation of motility and development in Myxococcus xanthus

The paper identifies and characterizes three PilZ domain proteins in Myxococcus xanthus, showing they have distinct roles in regulating motility and development through c-di-GMP signaling.