NMPylation and de-NMPylation of SARS-CoV-2 Nsp9 by the NiRAN domain
B. Wang, D. Svetlov, I. Artsimovitch
This study investigates NMPylation and de-NMPylation of SARS-CoV-2 Nsp9 by the NiRAN domain, showing that Nsp12 NMPylates native Nsp9 and that NiRAN residues are essential for this process.
bioRxiv · Jun 13, 2021Biochemistry