BioengineeringbioRxivPreprint
Chronic Prestress Regulation of Micro-Heart Muscle Physiology
D. W. Simmons, D. R. Shuftan, J. Guo…·N. Huebsch
This study investigates how tissue geometry affects electrophysiology in engineered heart muscle tissues, revealing a prestress threshold for sodium channel function and the role of PKP2 in electrical remodeling.
DOI 10.1101/2022.07.23.501265