Heterotypic responses against nsp12/nsp13 from prior SARS-CoV-2 infection associates with lower subsequent endemic coronavirus incidence
D. J. Bean, J. Monroe, Y. M. Liang, E. Borberg, Y. Senussi, Z. Swank, S. Chalise, D. Walt, J. Weinberg, M. Sagar
The paper finds that prior SARS-CoV-2 infection, but not vaccination, reduces subsequent symptomatic endemic coronavirus incidence and is associated with stronger CD8+ T cell responses to non-structural proteins.
bioRxiv · Oct 23, 2023 · PreprintImmunology